The Health Map for Cancer
A Health Map is the navigation layer above the Topics. It shows the full path, the cross-area benefits, common mistakes, the contexts in which it applies, where experts disagree at the area level, and what is changing now.
Is cancer fundamentally a metabolic disease or a genetic disease?
Mainstream: Mainstream oncology centers on genetic mutation accumulation as the primary mechanism of cancer initiation and progression — supported by decades of molecular biology, sequencing data, and the targeted therapies that exploit specific mutations.
Contested: The metabolic theory of cancer (Seyfried-style framings) argues mitochondrial dysfunction is the primary cause and that cancer should be treated as a metabolic disease. The Warburg effect (cancer cells preferentially use glucose) is well-established cell biology, but the broader primary-driver positioning departs from mainstream oncology.
What survives: Both metabolic and genetic factors matter; cancer biology is integrative. The clinical application of metabolic interventions as cancer treatment is preliminary, not mainstream. For active cancer, standard oncology should not be replaced by metabolic-theory-driven protocols.
The full Roadmap applies this pattern across every area-level tension. Path, Mistakes, Context, and What's changing now follow the same approach.
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